[Use of therapeutic polycomponent vaccine 'Immunovac VP-4' for the treatment of chronic bacterial prostatitis]

Autor: V M, Bondarenko, A E, Vershinin, V M, Kucherskiĭ, V G, Mitkov, N E, Klimova, E A, Kurbatova, N B, Egorova
Rok vydání: 2004
Předmět:
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii. (3)
ISSN: 0372-9311
Popis: A complex of clinical and laboratory examinations of patients with bacterial chronic prostatitis was carried out. The patients were divided into two groups: 55 patients treated by the method of immunotherapy and 20 patients (controls) undergoing basic therapy. Immunotherapy was carried out with the use of polycomponent vaccine VP-4 containing Staphylococcus aureus, Klebsiella pneumoniae, Proteus vulgaris and Escherichia coli antigens. Vaccinal therapy was indicated in cases with infection focus associated with opportunistic bacteria, a prolonged torpid course of prostatitis and when different schemes of etiotropic therapy proved to be ineffective. The vaccine was introduced in 4 or 5 subcutaneous injections at an interval of 5-7 days. The study revealed that in cases of chronic prostatitis accompanied by microecological and immune disturbances the use of complex therapy allowed to achieve good clinical and laboratory results in 91% of the patients. In the patients undergoing immunotherapy the elimination of opportunistic bacteria from the urogenital tract and the restoration of affected microflora occurred.
Databáze: OpenAIRE