Functional Study of

Autor: Lucas, Lorenzon, José C, Quilles, Gustavo Daniel, Campagnaro, Lissur, Azevedo Orsine, Leticia, Almeida, Flavio, Veras, Rubens Daniel, Miserani Magalhães, Juliana, Alcoforado Diniz, Tiago, Rodrigues Ferreira, Angela, Kaysel Cruz
Rok vydání: 2022
Předmět:
Zdroj: ACS infectious diseases. 8(3)
ISSN: 2373-8227
Popis: In trypanosomatids, regulation of gene expression occurs mainly at the posttranscriptional level, and RNA-binding proteins (RBPs) are key players in determining the fates of transcripts. RBPs are targets of protein arginine methyltransferases (PRMTs), which posttranslationally regulate the RNA-binding capacity and other RBP interactions by transferring methyl groups to arginine residues (R-methylation). Herein, we functionally characterized the five predicted PRMTs in
Databáze: OpenAIRE