[Cyclic hydrazides. II. (1) Synthesis of 3-aminopyrazolo[1,2-b]hthalazine-1(1H),5(10 H)-diones]
| Autor: | G, Winters, N, Di Mola, E, Oppici, G, Nathansohn |
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| Rok vydání: | 1975 |
| Předmět: | |
| Zdroj: | Il Farmaco; edizione scientifica. 30(08) |
| ISSN: | 0430-0920 |
| Popis: | The synthesis is described of a number of 3-aminopyrazolo[1,2-b]phthalazine-1(1H),5(10H)-diones (I) differently substituted on the amino group and in position 2, through condensation of alpha-chloro-beta-chlorocarbonylenamines (IV) with the 3,4-dihydrophthalazin-1(2H)-one (III). Alternatively cyanoacetylchlorides are condensed with (III) giving directly the 3-aminopyrazolo[1,2-b]phthalazine-1(1H),5(10H)-diones with the primary amino function (VII). |
| Databáze: | OpenAIRE |
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