[Optimal extraction technology for genistein in Flemingia macrophylla with response surface method]

Autor: Ying-Feng, Niu, Zhong-Lian, Zhang, Hai-Tao, Li, Yan-Hong, Guan, Chao-Zhong, Peng, Li-Xia, Zhang
Rok vydání: 2014
Předmět:
Zdroj: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 36(10)
ISSN: 1001-4454
Popis: To optimize extraction techniques for genistein in Flemingia macrophylla by using response surface method.Based on the single factor experiment, extraction temperature, extraction time and solvent ratio served as the response factor while the extraction rate of genistein served as the response value. Based on multiple linear regression and binomial expression, response surface method was employed to optimize the extracting process, and predicative analysis was conducted.The effects of factors in the descending order were as follows: extraction temperature, extraction time and solvent ratio. The optimal extraction technology was as follows: extraction temperature 80 degrees C, extraction time 3.5 h and solvent ratio 20 mL/g. Under these conditions, the extraction rate of genistein reached 0.161 mg/g.The results are agreed with model predictions. The technology can be used as the extraction process of genistein in Flemingia macrophylla.
Databáze: OpenAIRE