A comparative study of amoxicillin, clindamycin and chlorhexidine in the prevention of post-extraction bacteraemia
| Autor: | Breminand, Maharaj, Yacoob, Coovadia, Ahmed C, Vayej |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male bacteraemia Adolescent Endocarditis infective endocarditis Clindamycin Cardiovascular Topics Chlorhexidine Amoxicillin Streptococcus Bacteremia Antibiotic Prophylaxis Middle Aged antibiotics Young Adult Postoperative Complications Treatment Outcome Streptococcal Infections Tooth Extraction Humans Female prophylaxis dental extraction Aged |
| Zdroj: | Cardiovascular Journal of Africa |
| ISSN: | 1680-0745 |
| Popis: | We evaluated some of the regimens recommended for the antimicrobial prophylaxis of infective endocarditis prior to dental extraction in 160 patients. Group A patients served as the control group, group B subjects rinsed their mouths with chlorhexidene, group C subjects took 3 g amoxicillin orally and group D patients took 600 mg clindamycin orally. The proportion of patients who had post-extraction bacteraemia in groups A, B, C and D was 35, 40, 7.5 and 20%, respectively. The differences between the control and amoxicillin groups (p = 0.003) and between the chlorhexidine and amoxicillin groups (p = 0.0006) were statistically significant. Streptococci were not isolated in any patients in the amoxicillin and clindamycin groups. In our study, none of the regimens were effective in preventing post-extraction bacteraemia. |
| Databáze: | OpenAIRE |
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