| Popis: |
The associations of breastfeeding and early childhood caries (ECC) risk have been evaluated in several epidemiological studies with conflicting results. We performed an update meta-analysis to estimate the association of feeding patterns, breastfeeding durations and ECC risk.Studies were identified through searching Pubmed, Web of Science, and Embase from January 1990 to December 2015.Thirty-five studies involving 73,401 participants aged 0-71 months were included. The overall analysis showed children ever breastfed had a reduced risk of ECC compared with those never breastfed (OR=0.77, 95% CI: 0.61-0.97, p=0.026). Subgroup analysis revealed ever breastfeeding significantly reduced ECC risk for the studies with 3-6 years old children (OR=0.70, 95% CI: 0.54-0.90, p=0.005), with sample size500 subjects (OR=0.63, 95% CI: 0.46-0.87, p=0.004), with Newcastle-Ottawa Scale (NOS) score=6 (OR=0.66, 95% CI: 0.46-0.94, p=0.023), published after 2010 (OR=0.50, 95% CI: 0.30-0.82, p=0.006), with adjusted OR (OR=0.40, 95% CI: 0.18-0.88, p=0.023). Exclusive breastfeeding did not significantly decrease ECC risk compared with bottle feeding (OR=0.68, 95% CI: 0.35-1.31, p=0.248). The children breastfed=12 months significantly increased ECC risk compared with those breastfed12 months (OR=1.86, 95% CI: 1.37-2.52, p0.001). Whereas, children breastfed=6 months did not significantly increase ECC risk compared with those breastfed6 months (OR=1.13, 95% CI: 0.83-1.53, p=0.428).Our analysis suggests ever breastfeeding may protect children from ECC, and breastfeeding duration=12 months is associated with higher ECC risk. Additional large cohort studies are required to illustrate the relationship in further study. |
