Novel peptide inhibitor of dipeptidyl peptidase IV (Tyr-Pro-D-Ala-NH

Autor:	M, Salaga, A, Binienda, P, Draczkowski, P, Kosson, R, Kordek, K, Jozwiak, J, Fichna
Rok vydání:	2018
Předmět:	Male Mice Inbred C57BL Dipeptidyl-Peptidase IV Inhibitors Disease Models Animal Mice Dipeptidyl Peptidase 4 Anti-Inflammatory Agents Animals Colitis Peptides
Zdroj:	Peptides. 108
ISSN:	1873-5169
Popis:	Protease inhibition has become a new possible approach in the inflammatory bowel disease (IBD) therapy. A serine exopeptidase, dipeptidyl peptidase IV (DPP IV) is responsible for inactivation of incretin hormone, glucagon-like peptide 2 (GLP-2), a potent stimulator of intestinal epithelium regeneration and growth. Recently we showed that the novel peptide analog of endomorphin-2, EMDB-1 (Tyr-Pro-D-ClPhe-Phe-NH
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::491dd5e0e476c73f465d611003dcb9f5 https://pubmed.ncbi.nlm.nih.gov/30179653 Zobrazit plný text záznamu Full Text from ScienceDirect