[The systems of molecular genetic markers under cancer of stomach]

Autor:	M V, Nemtsova, I I, Bykov, N V, Tchekinova, D V, Zaletaev, A I, Glikhov, T V, Khorobrykh
Rok vydání:	2014
Předmět:	Gene Expression Regulation Neoplastic Stomach Neoplasms Biopsy Biomarkers Tumor Humans DNA Methylation Promoter Regions Genetic
Zdroj:	Klinicheskaia laboratornaia diagnostika. (11)
ISSN:	0869-2084
Popis:	The study was organized to investigate the anomalous methylation of genes NA?1, RASSF1A, MLH1, N33, DAPK, the expression of genes hTERT. metalloproteinase MMP7, MMP9, survivin. COX-2, p53. The activity of telomerase in 106 samples of stomach tumors taken through intra-operation way and 53 samples of stomach tumors taken through endoscopic way and 50 samples of biopsy taken from patients with chronic calculous cholecystitis (comparison group) was analyzed too. These changes can be used as additional markers both in diagnostic of cancer of stomach and dynamic monitoring of operated patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4917ec1e6ae4f9cab8f25e7092c7977c https://pubmed.ncbi.nlm.nih.gov/24640104 Zobrazit plný text záznamu