[Methodological aspects of evaluation of potential lipid capacity for peroxidation from the serum levels of TBA-active products during iron ion stimulation]

Autor: A I, Kulikova, F A, Tugusheva, I M, Zubina, I N, Shepilova
Rok vydání: 2008
Předmět:
Zdroj: Klinicheskaia laboratornaia diagnostika. (5)
ISSN: 0869-2084
Popis: The authors propose a simple and reproducible procedure for using iron ions to stimulate serum lipid peroxidation, with TBA-active products being further determined. The procedure determines the reserve of lipids that can be oxidized during oxidative stress. A combination of direct studies and correlation analysis suggests that low-density lipoproteins and very low-density lipoproteins are the major substrates for lipid peroxidation while high-density lipoproteins show a high resistance to this process. The presented procedure may be used to monitor lipid peroxidation in various conditions and upon various exposures in common laboratory practice.
Databáze: OpenAIRE