Exploration of the cellular effects of the high-dose, long-term exposure to coffee roasting product furan and its by-product

Autor:	João S, Teodoro, Rui, Silva, António, Aguiar, Abílio J F N, Sobral, Anabela P, Rolo, Carlos M, Palmeira
Rok vydání:	2020
Předmět:	Aldehydes Hot Temperature Protein Carbamylation Time Factors Dose-Response Relationship Drug Cell Survival Coffee Rats Oxidative Stress Adenosine Triphosphate Species Specificity 8-Hydroxy-2'-Deoxyguanosine Seeds Hepatocytes Animals Humans Cooking Furans Cells Cultured DNA Damage
Zdroj:	Toxicology mechanisms and methods. 30(7)
ISSN:	1537-6524
Popis:	Coffee is the most popular hot beverage and caffeine is the most used psychoactive drug in the world. Roasting of coffee beans leads to the generation of minute quantities of undesirable compounds, such as furan. It is now thought that the toxicity of furan derives from its processing by CYP450 family of detoxifying enzymes, leading to the formation of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4912853f94227173bf2c81c620d3c13c https://pubmed.ncbi.nlm.nih.gov/32544017 Zobrazit plný text záznamu