Lectin-binding affinities of human breast tumors

Autor:	C J, Louis, T, Sztynda, Z M, Cheng, R G, Wyllie
Rok vydání:	1983
Předmět:	Microscopy Fluorescence Lectins Receptors Mitogen Humans Breast Neoplasms Female Breast Fibrocystic Breast Disease Fluoresceins Fluorescein-5-isothiocyanate Thiocyanates Fluorescent Dyes
Zdroj:	Cancer. 52(7)
ISSN:	0008-543X
Popis:	Paraffin-embedded sections from a variety of breast lesions were stained with a number of lectins labeled with fluorescein isothiocyanate and examined by fluorescence microscopy: 95 non-neoplastic tissues and 69 malignant tumors were examined. Lectin binding was demonstrated in all malignant tumors, the fluorescence being confined to the plasma membrane of the tumor cells. Normal and hyperplastic tissues either failed to stain or showed a grossly diminished level of fluorescence. The significance of the staining reaction is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4909c77eab234cc45874c55a438cfda4 https://pubmed.ncbi.nlm.nih.gov/6411323 Zobrazit plný text záznamu Plný text