The correlation between striatal and cortical binding ratio of

Autor:	Julia, Sauerbeck, Kazunari, Ishii, Chisa, Hosokawa, Hayato, Kaida, Franziska T, Scheiwein, Kohei, Hanaoka, Axel, Rominger, Matthias, Brendel, Peter, Bartenstein, Takamichi, Murakami
Rok vydání:	2018
Předmět:	Cerebral Cortex Lewy Body Disease Male Amyloid Aniline Compounds Parkinson Disease Corpus Striatum Thiazoles Alzheimer Disease Positron-Emission Tomography Humans Cognitive Dysfunction Female Frontotemporal Lobar Degeneration Radiopharmaceuticals Aged Retrospective Studies
Zdroj:	Annals of nuclear medicine. 32(6)
ISSN:	1864-6433
Popis:	In subjects with amyloid deposition, striatal accumulation ofSeventy-three subjects who complained of cognitive disturbance underwent dynamic PiB-PET studies and showed positive PiB accumulation were retrospectively selected. These subjects included 34 AD, 26 mild cognitive impairment, 2 frontotemporal lobar degeneration, 2 Parkinson's disease, 5 dementia with Lewy bodies, and 4 undefined diagnosis patients. Individual BPThere were highly significant correlations between striatal and prefrontal BPOur study demonstrated positive correlations in amyloid deposits between the striatum and other cortical areas with functional and anatomical links. The amyloid distribution in the brain is not random, but spreads following the functional and anatomical connections.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::48d7775820cf7ceb912c4c30742d8bcc https://pubmed.ncbi.nlm.nih.gov/29730823 Zobrazit plný text záznamu Full text from SpringerLink