Cerylimycins [corrected] A and B: antibacterial triterpenes from the new species Tricholoma sp. AU1

Autor:	Simon P B, Ovenden, Jin, Yu, Jill, Bernays, Soo San, Wan, Larissa J, Christophidis, Gian, Sberna, R Murray, Tait, Howard G, Wildman, Dominique, Lebeller, Denis, Platel, Tom W, May, Barbara M, Meurer-Grimes
Rok vydání:	2005
Předmět:	Molecular Structure Basidiomycota Gram-Negative Bacteria Australia Tumor Cells Cultured Humans Microbial Sensitivity Tests Drug Screening Assays Antitumor Gram-Positive Bacteria Nuclear Magnetic Resonance Biomolecular Triterpenes Anti-Bacterial Agents
Zdroj:	Journal of natural products. 68(3)
ISSN:	0163-3864
Popis:	To new triterpenes, trichomycins A (1) and B (2), were purified from the new species Tricholoma sp. AU1 by activity-guided fractionation following their antibacterial activity. The two compounds were found to have a hitherto unreported triterpenoid skeleton. The structures and relative stereochemistry of 1 and 2 were determined through extensive 2D NMR spectroscopy, while the inhibitory activity of 1 and 2 against two Gram-positive and two Gram-negative bacteria and a mammalian cell line was determined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4862f9e948cf29137966dbab8302b904 https://pubmed.ncbi.nlm.nih.gov/15787446 Zobrazit plný text záznamu