Analysis of DEXI/Dexi refines the organization of the mouse 7C and human 15q11--q13 imprinting clusters
| Autor: | M, Kelly, A J, Edgar, R, Wevrick |
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| Rok vydání: | 2001 |
| Předmět: |
Expressed Sequence Tags
Chromosomes Human Pair 15 Transcription Genetic Molecular Sequence Data Mice Inbred Strains Physical Chromosome Mapping Dexamethasone Evolution Molecular Mice Inbred C57BL Genomic Imprinting Mice Open Reading Frames Multigene Family Animals Humans RNA Messenger Angelman Syndrome Prader-Willi Syndrome |
| Zdroj: | Cytogenetics and cell genetics. 92(1-2) |
| ISSN: | 0301-0171 |
| Popis: | Identification of imprinted genes in the Prader-Willi/Angelman syndrome deletion region is complicated by the presence of large flanking repeats. While inactive copies of DEXI are located within the repeats, we have now localized the active DEXI gene to 15q11--q13 outside the PWS/AS deletion and Dexi to mouse chromosome 16, suggesting complex evolution of this genomic region in both species. |
| Databáze: | OpenAIRE |
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