Intimal-type primary sarcoma of the aorta. Report of a case with evidence of rhabdomyosarcomatous differentiation

Autor:	C, Miracco, L, Laurini, R, Santopietro, M M, De Santi, C, Sassi, E, Neri, F, Pepi, P, Luzi
Rok vydání:	1999
Předmět:	Male Microscopy Electron Rhabdomyosarcoma Biomarkers Tumor Humans Aorta Thoracic Cell Differentiation Sarcoma Tomography X-Ray Computed Tunica Intima Vascular Neoplasms Aged Aortic Aneurysm
Zdroj:	Virchows Archiv : an international journal of pathology. 435(1)
ISSN:	0945-6317
Popis:	We report an intimal sarcoma presenting as an aortic aneurysm. A 68-year-old man suffered from chest pain and speech disturbance. Computed tomography showed a sacciform aneurysm of the aorta, which was resected, revealing a polypoid tumour measuring 1.5x2x2.5 cm projecting into the lumen. This proved to be a poorly differentiated high-grade sarcoma having morphological, immunophenotypic and ultrastructural features consistent with rhabdomyosarcomatous differentiation. Primary sarcomas of the aorta are extremely rare. Many cases have been diagnosed as "intimal" on the basis of their site of origin, and they are not easy to classify from their histological pattern. Electron microscopy and the use of a more comprehensive panel of immunohistochemical markers should be applied in the histological classification of"intimal" sarcoma.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::483b70d81755aa9231ccaacf0e6908f2 https://pubmed.ncbi.nlm.nih.gov/10993285 Zobrazit plný text záznamu Full text from SpringerLink