[Severe bone malformations in fetal valproic acid disease]

Autor: G, Lorenzo Sanz, C, Serna Saugar, A, Quintana Castilla, C, Lozano Giménez, J M, Aparicio Meix
Rok vydání: 1993
Předmět:
Zdroj: Anales espanoles de pediatria. 39(1)
ISSN: 0302-4342
Popis: The dysmorphogenic and teratogenic effects of valproic acid, when administered to pregnant women, have been noted in several reports. We report the case of a 3-month-old infant with multiple congenital anomalies, including severe skeletal malformations, congenital heart defect and facial dysmorphism, whose mother was treated with valproic acid (1000 mg/day) throughout the pregnancy. This is the second published case reporting major skeletal malformations and supports the possible teratogenic effects of valproic acid.
Databáze: OpenAIRE