| Autor: |
Yamini, Krishnan, Gazel, S, Aswin, Joy, Sreedharan P, S, Reshmi J, S, Sandhya, S |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
The Gulf journal of oncology. 1(40) |
| ISSN: |
2078-2101 |
| Popis: |
The translocation t (12;17) (p13; q21) is a rare cytogenetic event most commonly described in pre-B- acute lymphoblastic leukaemia and acute myeloid leukaemia. We identified a child with an immunophenotype of Early T Cell Precursor Acute Lymphoblastic Leukaemia ETP- ALL having t (12;17) (p13; q21) translocation as the primary karyotypic anomaly. The association of t (12;17) (p13; q21) with ETP-ALL has not been described previously in literature. The possibility of it being a novel genetic abnormality or a part of the newly described entity of ETP/myeloid MPAL is being discussed. Detection of such abnormalities can alter the prognosis of ETP-ALL. Key words: ETP-ALL , t(12;17) (p13;q21) translocation, ETP- MPAL. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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