| Autor: |
Meng-zhong, Liu, Xiu-shen, Wang, Ling, Cai, Hui, Liu, Er-cheng, Chen, Nian-ji, Cui |
| Rok vydání: |
2005 |
| Předmět: |
|
| Zdroj: |
Zhonghua zhong liu za zhi [Chinese journal of oncology]. 27(2) |
| ISSN: |
0253-3766 |
| Popis: |
To analyze treatment and prognostic factors of 74 patients with dermatofibro-sarcoma protuberans (DFSP).From August 1990 to November 1999, 74 patients with DFSP confirmed pathologically were treated. There were 52 males and 22 females with a median age of 37 years (range 4 to 80 years) on diagnosis. Seventeen patients were treated by extensive excision and 2 by limited excision. Fifty-two patients had surgical resection alone (S), and 22 postoperative radiotherapy (S + R) of 50-70 Gy. The multivariate parameters were analyzed using Cox model. Kaplan-Meier and Log-Rank test were used to evaluate the results of the recurrence-free survival.The rate of recurrence was 28.4% for all patients. The 5-year recurrence-free survival rate (RFSR) was 66.6% and the 10-year RFSR was 52.5%. The 5-year and 10-year in the S group were 58.4% and 41.2%, compared with 90.0% and 83.3% in the S + R group (P0.05). The 5-year and 10-year RFSR in the pathologically positive margin group were 57.5% and 41.4% respectively, compared with the 75.0% and 56.6% in the pathologically negative group (P0.05). Multivariate analysis suggested radiotherapy and negative pathological margins were favorable prognostic factors.Post-operation radiotherapy and pathological margin are the independent prognostic factors. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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