[Glatiramer acetate (Copaxone) influence on different stages of multiple sclerosis pathogenesis]

Autor: T E, Shmidt, T D, Zhuchenko, N N, Iakhno
Rok vydání: 2003
Předmět:
Zdroj: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. (Spec No 2)
ISSN: 1997-7298
Popis: Multiple sclerosis (MS)--autoimmune disease of CNS, characterized by myelin destruction and axonal damage. The action of drugs recommended for its treatment [symbol: see text] aimy[symbol: see text] at the reduction of the autoimmune responses. These responses lead to the neurological damage. One of immunoregulators is glatiramer acetate--Copaxone. Copaxone acts at different phases of MS pathogenesis and probably has a neuroprotective action. Copaxone reduces the rate of relapses and leads to clinical stabilisation in cases of relapsing-remmiting MS. Its efficacy and safety has been confirmed in long-term clinical and MRI-trials. Copaxone has few side-effects that are non-significant.
Databáze: OpenAIRE