| Autor: |
T, Simonart, G D, Dobbeleer, M, Peny, I, Fayt, D, Parent, J, Vooren, J, Noel |
| Rok vydání: |
1999 |
| Předmět: |
|
| Zdroj: |
European journal of dermatology : EJD. 9(6) |
| ISSN: |
1167-1122 |
| Popis: |
We report on a lymphoedematous form of classic Kaposi's sarcoma (KS) in which characteristic purplish lesions were surrounded by atypical oedematous, flesh-coloured papules. Histological examination of these papular lesions revealed a proliferation of grouped, rather thick-walled capillaries with inflammatory infiltrates. Hot-start PCR amplification with KS 330-233 primer sequences demonstrated the presence of human herpesvirus 8 (HHV-8) sequences. In addition, cells isolated from these oedematous papules showed morphological and immunohistochemical features similar to those reported for KS-derived spindle cells. As a whole, these results suggest that these oedematous papular lesions represent pre-KS lesions and may expand the clinico-pathological spectrum of KS. The role of oedema in their induction is discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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