Triploidy in a growth discordant twin pregnancy after intracytoplasmic sperm injection treatment. Case report

Autor: Inanc, Mendilcioglu, Mualla, Ozcan, Gulseren, Bagci, Mehmet, Simsek, Sinan, Kursun, Guven, Luleci, Omur, Taskin
Rok vydání: 2004
Předmět:
Zdroj: Fetal diagnosis and therapy. 21(1)
ISSN: 1015-3837
Popis: We report on a case of a triploidy in one fetus of a twin pregnancy who presented with the findings of growth discordance.Three weeks' difference between fetuses in ultrasonographic measurements in the first trimester was observed in a twin pregnancy following intracytoplasmic sperm injection (ICSI) treatment for male infertility. Hydrocephaly developed in the growth-discordant fetus subsequently. Amniocentesis for both fetuses and selective feticide for the abnormal one was performed at 19 weeks' gestation through a single insertion. Fetal karyotype of the abnormal one was 69,XXX and the healthy one was 46,XX.Early developed growth discordance in a twin pregnancy may be a sign of chromosomal abnormality such as triploidy. Those cases should be karyotyped without delay to decrease preterm delivery risk of possible selective feticide.
Databáze: OpenAIRE