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The purpose of this prospective study was to compare the ovarian response and pregnancy outcomesbr /in the infertile women with endometrioma undergoing assisted reproductive technologies (ART) in twobr /groups, who were underwent laparoscopic cystectomy and received gonadotropin releasing hormone-agonistbr /(GnRH-agonist) and who only received GnRH-agonist without any surgery.br /Materials and Methods: In this prospective clinical trial study, 79 infertile women with asymptomatic endometriomasbr /cyst (2-6 cm) were enrolled and randomly assigned to two groups. First group underwent laparoscopicbr /cystectomy and received GnRH-agonist. Second group only received GnRH-agonist without any surgery. Followingbr /ovulation induction, all patients underwent intracytoplasmic sperm injection (ICSI). Different parametersbr /such as the number of retrieved oocytes and embryos; were made our outcomes that analyzed using SPSS.br /Results: The pregnancy rate, chemical and clinical, and live birth rate were higher in the combined group,br /although these differences were not statistically significant (48.48% vs. 30.8%, P=0.12, 36.36% vs. 25.6%,br /P=0.32, 36.36% vs. 23.1%, P=0.29). The number of injections, antral follicles, retrieved oocytes, mature oocytes,br /total embryos, transferred embryos and duration of stimulation were similar in two groups.br /Conclusion: Laparoscopic cystectomy followed by receiving GnRH-agonist improves pregnancy outcomes in endometriomabr /prior to treatment with ART (registration number: IRCT201106116689N2). |
