| Autor: |
N, Verzijl, J, DeGroot, E, Oldehinkel, R A, Bank, S R, Thorpe, J W, Baynes, M T, Bayliss, J W, Bijlsma, F P, Lafeber, J M, Tekoppele |
| Rok vydání: |
2000 |
| Předmět: |
|
| Zdroj: |
The Biochemical journal. |
| ISSN: |
0264-6021 |
| Popis: |
Non-enzymic modification of tissue proteins by reducing sugars, the so-called Maillard reaction, is a prominent feature of aging. In articular cartilage, relatively high levels of the advanced glycation end product (AGE) pentosidine accumulate with age. Higher pentosidine levels have been associated with a stiffer collagen network in cartilage. However, even in cartilage, pentosidine levels themselves represent |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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