| Autor: |
A A, Shandra, L S, Godlevskiĭ, A M, Mazarati, R F, Makul'kin |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Neirofiziologiia = Neurophysiology. 22(4) |
| ISSN: |
0028-2561 |
| Popis: |
The seizure activity was investigated on the model of pharmacological kindling which was induced by repeated picrotoxin injections in the subthreshold dose, after the tryptic fragment of T5 protein-human diazepam binding inhibitor (DBI) (10 micrograms) injection into a reticular part of substantia nigra. An increase in the seizure reaction and suppression of the antiseizure diazepam action were observed. Intranigral DBI injection induced no change in a threshold of "attacks" in rats which were induced through electric shocks delivered to animals with an electrode floor and no changes in antiaggressive diazepam action were observed under such conditions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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