Investigations on the Changes of Serum Proteins in Rabbits after

Autor: Shijun, Wang, Weilian, Yang, Wanling, Shi, Fuwei, Chen, Fanghua, Shen, Meiji, Zhang, Qiuxiang, Su, Chao, Shi, Qinyao, Yu, Tao, Chen
Rok vydání: 2022
Zdroj: Evidence-based complementary and alternative medicine : eCAM. 2022
ISSN: 1741-427X
Popis: There are few studies on protein phosphorylation in the process of snake poisoning. The purpose of this study was to investigate the toxic mechanism ofTheCompared to the control group, 77 differentially expressed proteins were observed in the model group. These proteins were closely associated with the complement and agglomerate cascade signaling pathways, the HIF signaling pathway, the pentose phosphate pathway, and the cholesterol metabolism signaling pathway. According to the results of network analysis, TF and SCL16A1 were determined as the core proteins, which were identified by the Western blotting assay.The present study provided valuable phosphorylation signal transduction resources for investigating the toxic mechanism and the therapies for
Databáze: OpenAIRE