[Double-blind controlled comparison of placebo and paracetamol in patients with G-6-PD deficiency]

Autor: F, Cottafava, S, Nieri, G, Franzone, M, Sanguinetti, L, Bertolazzi, G, Ravera
Rok vydání: 1990
Předmět:
Zdroj: La Pediatria medica e chirurgica : Medical and surgical pediatrics. 12(6)
ISSN: 0391-5387
Popis: In this study are reported 17 patients with G-6-PD deficiency. These subjects have been studied with double-blind trial between placebo and Paracetamol, looking for the possible hemolysis induced from drug in these children with G-6-PD deficiency. Hemolysis had been valued by various hematological parameters (Hb, erythrocyte count, reticulocytosis, bilirubinemia, haptoglobin, hemopexin, and survival of erythrocytes marked with Cr). The results (8 cases with placebo and 9 cases with paracetamol) demonstrate that paracetamol have not induced hemolysis in these G-6-PD deficient subjects.
Databáze: OpenAIRE