| Autor: |
Enrique, Norero, Eduardo, Viñuela, Sergio, Báez, Cristian, Martínez, Julio, Reyes, Rodrigo, Kusanovic, Marcel, Sanhueza, Gloria, Aguayo, Alfonso, Calvo, Rose Marie, Mege, Mario, Caracci, Alfonso, Díaz |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Revista medica de Chile. 139(8) |
| ISSN: |
0717-6163 |
| Popis: |
The diagnosis and treatment of periampullary tumors represents a challenge for current medicine.To review the results of pancreaticoduodenectomy (PDD) in the treatment of periampullary tumors and to identify risk factors that impact the long-term survival.We performed a retrospective study of patients who underwent a PDD for periampullary tumors between 1993 and 2009. We reviewed perioperative results and long term survival. We performed a multivariate analysis for long-term survival.A PDD was performed in 181 patients aged 58 ± 12 years (98 females). Pyloric preservation was done in 53% and a pancreatogastric anastomosis was used in 94% of cases. Morbidity was 62% and postoperative mortality was 5.5%. Pancreatic cancer was the most frequent pathological finding in 41%, followed by ampullary cancer in 28% and distal bile duct cancer in 16%. Median survival was 17 months, with a five years survival of 24%. Survival for ampullary tumors was 28 months with a five years survival of 32%. The median and five years survival were 14 months and 16% for bile duct cancer and 11 months and 14% for pancreatic cancer. Multivariate analysis identified tumor type (pancreas /bile duct) and lymph node dissemination as independent predictors of mortality.One quarter of patients experienced long term survival. Mortality predictors were tumor type and lymph node dissemination. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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