Adenosine Mediates Hypercapnic Response in the Rat Carotid Body via A

Autor: Joana F, Sacramento, Bernardete F, Melo, Sílvia V, Conde
Rok vydání: 2018
Předmět:
Zdroj: Advances in experimental medicine and biology. 1071
ISSN: 0065-2598
Popis: Adenosine is one of the key neurotransmitters involved in hypoxic signaling in the carotid body (CB), and it was recently found to have a modulatory role in mediating hypercapnic sensitivity in the CB. Herein we have investigated the contribution of adenosine to the hypercapnic response in the rat CB and studied the adenosine receptors responsible for this effect. Experiments were performed in Wistar rats. Adenosine release in normoxia (21% O
Databáze: OpenAIRE