| Autor: |
M J, Campbell, D W, Willis, M E, Hamrick, C K, Born |
| Rok vydání: |
1986 |
| Předmět: |
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| Zdroj: |
Research communications in chemical pathology and pharmacology. 51(1) |
| ISSN: |
0034-5164 |
| Popis: |
Application of a commercial acrylate sealer/finish to the floor of our animal quarters resulted in almost complete elimination of the positive chronotropic response of the hypoxic rat atria to isoproterenol. Forty-eight hours exposure to this sealer/finish decreased sensitivity to isoproterenol by approximately 1000-fold and decreased maximal response by 70%. The elimination of the response to isoproterenol was associated with the resin portion of the sealer/finish and was reversible on removal of the rats from exposure to the product. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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