| Autor: |
L B, Aksel'rod, L S, Arshinova, A I, Gaĭdenko, Ia B, Maksimovich, D M, Sukolovskaia |
| Rok vydání: |
1985 |
| Předmět: |
|
| Zdroj: |
Farmakologiia i toksikologiia. 48(5) |
| ISSN: |
0014-8318 |
| Popis: |
Experiments on 75 dogs with experimental myocardial infarction were made to study and compare the therapeutic effect of nicamag (a mixture of potassium and magnesium nicotinates) in a dose of 10 mg/kg, panangin and asparkam (potassium and magnesium aspartates). Nicamag rapidly precipitated postinfarction arrhythmia and made the ECG completely return to normal in the majority of cases. A beneficial effect of the drug on carbohydrate, energy and electrolyte metabolism in the myocardium was discovered to underlie the above-described action. Nicamag abruptly lowered the titers of cardial antibodies, increased the fibrinalytic activity of the blood which is accounted for by the effect of the anion--nicotinic acid. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
