Parenteral and enteral nutrition and the enterocutaneous fistula treatment. II. Factors influencing the outcome of treatment
| Autor: | E, Dárdai, S, Pirityi, L, Nagy |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Aged 80 and over Male Parenteral Nutrition Wound Healing Adolescent Fistula Ileal Diseases Age Factors Jejunal Diseases Middle Aged Skin Diseases Survival Rate Enteral Nutrition Postoperative Complications Treatment Outcome Intestine Small Intestinal Fistula Humans Surgical Wound Infection Female Duodenal Diseases Aged Retrospective Studies |
| Zdroj: | Acta chirurgica Hungarica. 32(4) |
| ISSN: | 0231-4614 |
| Popis: | An 18-year review of 64 patients treated with 71 postoperative enterocutaneous fistulas of the stomach /4/, duodenum /21/, jejunum /9/ and ileum /37/ was carried out to identify the factors affecting morbidity and mortality. Age, localization, output, inflammatory or malignant bowel disease, nutritional status and associated sepsis were analysed. The administration of total parenteral nutrition (TPN) or/and enteral nutrition (EN) as adjuvant therapy in the management of gastrointestinal fistulas increased the fistula closure rate (64%) and decreased mortality (33%). In patients over 65 years a rise in mortality rate (69%) was found. TPN and EN support yielded the best results in duodenal and jejunal fistula patients (closure rate 83% and 71%; respectively). In patients with high-output fistulas, inflammatory bowel disease and malignancy good results could be achieved with nutritional treatment. The presence of malnutrition had an adverse effect on the outcome in the non-TPN group with a mortality rate of 49%. In 43 patients severe septic complications occurred and 21 died due to septic multiple organ failure proved by autopsy. The overall mortality rate was 39%. Timing of fistula surgery had little impact on the fistula closure rate, but better results were obtained when reconstructive surgery was deferred beyond 6 weeks from fistula onset. Mortality has decreased since 1980. While many factors influence the outcome of fistula disease, adequate antiseptic treatment is assumed of primary importance. The nutritional therapy facilitated the spontaneous fistula healing and allowed the elective intestinal reconstruction to be scheduled at an optimal time. |
| Databáze: | OpenAIRE |
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