Fatal abdominal sarcomatosis secondary to gastrointestinal stromal tumor with bland histology

Autor:	Yasmin M, Elshenawy, Charles E, Ganote, Mousa A, Al-Abbadi
Rok vydání:	2009
Předmět:	Male Gastrointestinal Stromal Tumors Multiple Organ Failure Biopsy Needle Ascites Sarcoma Middle Aged Immunohistochemistry Fatal Outcome Disease Progression Humans Mesentery Neoplasm Invasiveness Autopsy Emergency Service Hospital Tomography X-Ray Computed Peritoneal Neoplasms Neoplasm Staging
Zdroj:	Saudi medical journal. 30(11)
ISSN:	0379-5284
Popis:	Fatal abdominal sarcomatosis is a rare complication secondary to gastrointestinal stromal tumor (GIST) arising from the small intestine. Here, we describe a 49-year-old man who presented with massive ascites and multiple mesenteric solid masses. Autopsy showed large necrotic mass (19 x 14 x 8.0 cm) surrounding the terminal ileum with multiple smaller nodules on the omentum and mesentery. Histological examination revealed highly cellular, predominantly bland, spindle cells with low mitotic activity. Gastrointestinal stromal tumor was confirmed by strong positive staining for c-KIT (CD 117). Our case is an example of fatal intra-abdominal sarcomatosis of GIST where the histological features were essentially bland.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::439801e71b760b82cd1c1ac4b2511a50 https://pubmed.ncbi.nlm.nih.gov/19882063 Zobrazit plný text záznamu