| Autor: |
Yong-jie, Ma, Yan-hong, Yuan, Li-qin, Xie, Ying-hui, Li, Yu-min, Wan, Zhi-zheng, Shi |
| Rok vydání: |
2003 |
| Předmět: |
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| Zdroj: |
Hang tian yi xue yu yi xue gong cheng = Space medicinemedical engineering. 16(4) |
| ISSN: |
1002-0837 |
| Popis: |
To investigate the effects of simulated weightlessness and mechanical loading on bone interstitial fluid flow.Thirty-six male Sprague-Dawley [correction of Spargue-Danley] rats were divided into 3 groups: the control group, the tail-suspension group, and the tail-suspension plus mechanical loading group, with four rats in each group. All the rats were injected via a lateral tail vein with horseradish peroxidase on the 21st day of the experiment. Tibial tissue specimens were explanted, fixed, decalcified and cut into 30 micrometers frozen sections 3 h after the intravenous injection.There were less peroxidase reaction product in the bony matrix and bone lacunae in tail-suspended rats than the control and tail-suspended plus mechanical loading rats.Tail-suspension decreased fluid movement through the bone, while mechanical loading increased it. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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