Pulmonary function changes in normal rats induced by antibody against rat IgE

Autor:	F B, Casey, B E, Abboa-Offei
Rok vydání:	1979
Předmět:	Time Factors Bronchial Spasm Dose-Response Relationship Drug respiratory system Immunoglobulin E respiratory tract diseases Antibodies Anti-Idiotypic Rats Disease Models Animal Cromolyn Sodium Animals Pulmonary Ventilation Lung Compliance Research Article
Zdroj:	Clinical and experimental immunology. 36(3)
ISSN:	0009-9104
Popis:	Changes in pulmonary function, as measured by airway conductance and dynamic compliance, in normal rats have been provoked by the administration of a rabbit antisera prepared against rat IgE myeloma protein. The response is specific in that neither anti-IgG nor normal rabbit serum induced pulmonary changes. Pre-treatment with disodium cromoglycate inhibits the bronchospasm in a dose related manner. In addition, drug protection can be demonstrated with as long 1 hr pre-dosing.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::434595294319a649cb06aa9f6b039552 https://pubmed.ncbi.nlm.nih.gov/114348 Zobrazit plný text záznamu Plný text ve formátu PDF