| Autor: |
E J, Nevins, R, Rao, J, Nicholson, K D, Murphy, A, Moore, H L, Smart, N, Stephens, C, Grocock, A, Kaul, R T, Gunasekera, M N, Hartley, N R, Howes |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Ann R Coll Surg Engl |
| ISSN: |
1478-7083 |
| Popis: |
INTRODUCTION: The incidence of delayed gastric emptying (DGE) following oesophagogastrectomy with gastric conduit reconstruction is reported to be between 1.7% and 50%. This variation is due to differing practices of intraoperative pylorus drainage procedures, which increase the risk of postoperative biliary reflux and dumping syndrome, resulting in significant morbidity. The aim of our study was to establish rates of DGE in people undergoing oesophagogastrectomy without routine intraoperative drainage procedures, and to evaluate outcomes of postoperative endoscopically administered Botulinum toxin into the pylorus (EBP) for people with DGE resistant to systemic pharmacological treatment. METHODS: All patients undergoing oesophagogastrectomy between 1 January 2016 and 31 March 2018 at our unit were included. No intraoperative pyloric drainage procedures were performed, and DGE resistant to systemic pharmacotherapy was managed with EBP. RESULTS: Ninety-seven patients were included. Postoperatively, 29 patients (30%) were diagnosed with DGE resistant to pharmacotherapy. Of these, 16 (16.5%) were diagnosed within 30 days of surgery. The median pre-procedure nasogastric tube aspirate was 780ml; following EBP, this fell to 125ml (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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