Autor: |
Emily A, Vucic, Kelsie L, Thu, Keith, Robison, Leszek A, Rybaczyk, Raj, Chari, Carlos E, Alvarez, Wan L, Lam |
Rok vydání: |
2012 |
Předmět: |
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Zdroj: |
Genome research. 22(2) |
ISSN: |
1549-5469 |
Popis: |
The genomics era has yielded great advances in the understanding of cancer biology. At the same time, the immense complexity of the cancer genome has been revealed, as well as a striking heterogeneity at the whole-genome (or omics) level that exists between even histologically similar tumors. The vast accrual and public availability of multi-omics databases with associated clinical annotation including tumor histology, patient response, and outcome are a rich resource that has the potential to lead to rapid translation of high-throughput omics to improved overall survival. We focus on the unique advantages of a multidimensional approach to genomic analysis in this new high-throughput omics age and discuss the implications of the changing cancer demographic to translational omics research. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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