Glycogen metabolism during human liver development

Autor: B G, Devi, C M, Habeebullah, P D, Gupta
Rok vydání: 1992
Předmět:
Zdroj: Biochemistry international. 28(2)
ISSN: 0158-5231
Popis: Development of enzymes of glycogen metabolism in human fetal and neonatal liver was investigated. Glycogen was present in quantitatable amount from early gestational age onwards; however, ultrastructurally it could not be detected earlier than 20 weeks. Increase in glycogen synthetase a activity during 21-36 weeks of gestation subsequently resulted in glycogen accumulation. A rapid degradation of this glycogen storage, at birth, was accompanied by an elevation in glycogen phosphorylase a activity. The present investigation to be the first to provide a complete profile of glycogen storage and differentiation of glycogen metabolising enzymes in preparing the prenatal fetus for its independent nutritional life.
Databáze: OpenAIRE