| Autor: |
M, Yücel, W J, Brewer, B J, Harrison, A, Fornito, G J, O'Keefe, J, Olver, A M, Scott, G F, Egan, D, Velakoulis, P D, McGorry, C, Pantelis |
| Rok vydání: |
2007 |
| Předmět: |
|
| Zdroj: |
Acta psychiatrica Scandinavica. 115(2) |
| ISSN: |
0001-690X |
| Popis: |
Anterior cingulate (ACC) hypo-activity is commonly observed in chronically ill schizophrenia patients. However, it is unclear whether this is secondary to persistent illness and/or medication.We examined eight antipsychotic-naïve first-episode patients and matched healthy controls undergoing PET scanning while performing the Stroop task.Group-averaged and single-subject analyses showed ACC activation in both controls and patients, albeit in different sub-regions (paracingulate and cingulate respectively). A direct comparison revealed relative under-activity of the left paracingulate cortex in patients.These findings suggest that the more pervasive hypo-activation observed in chronic patients may be secondary to persistent illness and/or medication. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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