| Autor: |
S, Borrelli, R, Minutolo, M, Calabria, M, Grimaldi, R, Di Pietro, G, Donnarumma, P L, D'Angio', G, Conte, L, De Nicola |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia. 26(3) |
| ISSN: |
0393-5590 |
| Popis: |
Resistant hypertension is defined as blood pressure that remains above the target of140/90 mm Hg in the general population and130/80 mm Hg in people with diabetes mellitus or chronic kidney disease (CKD) in spite of the use of at least three full-dose antihypertensive drugs including a diuretic, or as blood pressure that reaches the target by means of four or more drugs. Hypertension is a frequent complication in CKD and a determining factor in the progression of renal damage, especially in proteinuric and diabetic patients, as well as contributing to a high cardiovascular risk. Clinical practice guidelines recommend blood pressure levels below 130/80 mm Hg in all CKD patients, but the target is reached in only a small proportion (10-20%), both in nephrology and non-nephrology settings. The resistance to antihypertensive treatment may be considered one of the causes of the poor achievement of blood pressure targets in CKD patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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