| Autor: |
A-M, Rouxel, A-M, Roguedas, R, Descourt, L, Misery |
| Jazyk: |
francouzština |
| Rok vydání: |
2008 |
| Předmět: |
|
| Zdroj: |
Annales de dermatologie et de venereologie. 135(11) |
| ISSN: |
0151-9638 |
| Popis: |
Erlotinib (Tarceva) belongs to the family of epidermal growth receptor factor (EGFR) inhibitors. Used in the treatment of some cancers, it is responsible for several cutaneous side effects. We report a case of hand-foot syndrome, which has not previously been described with this drug to our knowledge.A 65-year-old patient was given erlotinib for lung cancer and after the first month of treatment, he developed severe hand-foot syndrome.Hand-foot syndrome consists of abrupt bilateral and painful acral erythema associated with dysesthesia. It is a dose-dependent side effect of certain cytostatic drugs. It may sometimes require withdrawal of the causative drug. Care must be taken to identify the early signs of hand-foot syndrome in patients treated with erlotinib. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect