| Autor: |
M I, Lusida, Soetjipto, R, Handajani, C A, Nidom, Soemarto, S, Darmadi, P, Adi, M, Fujii, T, Fujita, S, Ishido, H, Hotta |
| Rok vydání: |
2000 |
| Předmět: |
|
| Zdroj: |
Japanese journal of infectious diseases. 53(2) |
| ISSN: |
1344-6304 |
| Popis: |
The viral load of different hepatitis C virus (HCV) subtypes, including the globally distributed HCV-1b and the unique Indonesian subtype HCV-1c, was analyzed using serum samples obtained from Indonesian blood donors and patients with chronic liver disease. The mean viral load of HCV-1c was comparable with that of HCV-1b, suggesting that HCV-1c is as pathogenic as HCV-1b. On the other hand, the mean viral load of HCV-2a was lower than that of HCV-1b or HCV-1c, with this result being consistent with previous observations. Interestingly, some HCV-2a strains were associated with a high viral load that was almost equivalent to that of HCV-1b and HCV-1c. This result implies the possibility that there exists a minor fraction of HCV-2a strains that cause higher levels of viremia compared with the majority of ordinary HCV-2a strains. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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