[Prevention of tension type headache with topiramate]

Autor: Anka, Aleksić-Shihabi, Gordana, Lojen, Vlasta, Vuković
Rok vydání: 2008
Předmět:
Zdroj: Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti. 62(2)
ISSN: 1330-0164
Popis: The aim of this study was to assess the efficacy of topiramate in the prevention of tension type headache. Tension type headache is the most common primary headache; the 1-year prevalence is 38%. Tension type headache often causes reduced quality of life.In this study 51 patients were included; the dose of topiramate was gradually increased to 100 mg and patients were followed up for 6 months. The number of days and decrease in headache intensity were measured by the Visual Analog Scale (VAS) from 1 to 10 before and with therapy.Study results showed a statistically significant decrease in the number of days with headache: the mean number of days before therapy was 13.25 and with therapy 8.65, (p=0,0001). A statistically significant decrease in headache intensity was also observed by VAS scale: before therapy 6.27 and with therapy 3.33 (p=0.0001).This study showed topiramate to be efficient in the prevention of tension type headache.
Databáze: OpenAIRE