[Immortalization of cultured cells by the Ha-rasEJ oncogene and expression of a gene of biogenetic value]

Autor: F, Montandon, H, Cao, M, Dreano, P, Padieu
Jazyk: francouzština
Rok vydání: 1992
Předmět:
Zdroj: Comptes rendus des seances de la Societe de biologie et de ses filiales. 186(5)
ISSN: 0037-9026
Popis: The double recombination into NIH-3T3 cells of the cloned Ha-rasEJ oncogene and the cDNA gene of the human growth hormone (hGH) under the control of a heat inducible promoter (hsp70) allowed hGH production either in vitro using the mass culture of engineered cells in biogenerators, or in vivo after xeno-transplantation of the cells into an animal host. Therefore the in vivo synthesized hGH induced the production of anti-hGH polyclonal antibodies.
Databáze: OpenAIRE