Black and white patients response to antidepressant treatment for major depression
Autor: | R V, Varner, P, Ruiz, D R, Small |
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Rok vydání: | 1998 |
Předmět: |
Adult
Male Psychiatric Status Rating Scales Depressive Disorder Dose-Response Relationship Drug Body Weight Black People Antidepressive Agents Tricyclic Length of Stay Middle Aged White People 1-Naphthylamine Sex Factors Treatment Outcome Pharmacogenetics Fluoxetine Sertraline Ambulatory Care Humans Female Selective Serotonin Reuptake Inhibitors Retrospective Studies |
Zdroj: | The Psychiatric quarterly. 69(2) |
ISSN: | 0033-2720 |
Popis: | Differences in response to psychopharmacologic agents according to race has so far primarily focused on investigations related to the response of Asian-American patients to neuroleptics and lithium. In this article, we present evidence which depicts that black patients need lower doses of tricyclic antidepressants (TCAs) than white patients to attain a similar response in the treatment of major depression. Likewise, we also advance that black patients might need lower doses of selective serotonin re-uptake inhibitor antidepressants (SSRIs) than white patients to attain a similar response in the treatment of major depression. Further studies are suggested to confirm these findings. |
Databáze: | OpenAIRE |
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