[Oral ciprofloxacin therapy in juvenile patients with cystic fibrosis--results of a prospective pilot study]

Autor: V, Sollich, E, Klöditz, R, Schuster, W, Handrick, S, Brömme, W, Rumler, R, Patsch, H, Kharari, F B, Spencker
Jazyk: němčina
Rok vydání: 1993
Předmět:
Zdroj: Kinderarztliche Praxis. 61(6)
ISSN: 0023-1495
Popis: Efficacy and safety of oral ciprofloxacin were studied in a prospective study at three cystic fibrosis centres, covering 24 in-patients suffering from cystic fibrosis and acute bronchopulmonary exacerbation. The patients were between 10 and 17 years of age. Pseudomonas infection was present in 75% of these patients. Despite frequent persistence of the pathogens, clinical improvement was noted in 75% of the treated children. A definite increase of the average MIC was not seen in 20 cases of persisting strains. No serious side effects occurred during the 14-day oral treatment course. Ciprofloxacin is a useful alternative to conventional parenteral treatment with antibiotics in patients suffering from cystic fibrosis and infections of the airways.
Databáze: OpenAIRE