[Spinal cord injury in multiple myeloma]

Autor: Iu S, Martynov, V K, Orlov, D E, Iarikov, N E, Andreeva, E I, Sonina, E L, Sokov, E V, Malkova, N V, Norzdriukhina, N A, Shuvakhina
Rok vydání: 1998
Předmět:
Zdroj: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 98(11)
ISSN: 1997-7298
Popis: Myelomic spinal cord damage may be a result of both its compression and vascular disorders (squeezing of an artery, disorders of venous outflow). Diagnosis is based on evaluation of the following signs: normochromic anemia; increase of ESR, total protein and calcium levels; discovery of M-gradient in protein fractions of gamma-zone; multiple regions of destruction in spondylogramme. In doubtful cases magneto-resonance and computer tomography were the most informative. Highly effective was therapy with intensive chemoprogramme including either a range of preparations (alkeran, BGNU, cyclophosphan, adriblastina, prednisolon) or a combination of polychemotherapy with irradiation. The operation was indicated in both insufficiency of conservative therapy and increasing of the symptoms of the damage.
Databáze: OpenAIRE