A Genome-Wide Screen for Wortmannin-Resistant Mutants in

Autor: Merve, Yılmazer, Burcu, Kartal, Çağatay, Tarhan, Ilayda, Özarabacı, Sedef, Akçaalan, Egemen, Özkan, Semian, Karaer Uzuner, Ercan, Arıcan, Bedia, Palabıyık
Rok vydání: 2019
Předmět:
Zdroj: DNA and cell biology. 38(12)
ISSN: 1557-7430
Popis: Complex human diseases such as metabolic disorders, cancer, neurodegenerative diseases, and mitochondrial dysfunctions arise from the biochemical or genetic defects in various cellular processes. Therefore, it is important to understand which metabolic processes are affected by which cellular impairment. Because genome-wide screening of mutant collections (haploid/diploid deletion library) provides important clues for the understanding of conserved biological processes and for finding potential target genes, we screened the haploid mutant collection of
Databáze: OpenAIRE