Rad5, HLTF, and SHPRH: A Fresh View of an Old Story

Autor:	Menattallah, Elserafy, Arwa A, Abugable, Reham, Atteya, Sherif F, El-Khamisy
Rok vydání:	2018
Předmět:	Ubiquitin-Protein Ligases DNA Helicases SHPRH HLTF Article DNA-Binding Proteins RAD5 Gene Expression Regulation HIV-1 Animals Humans cancer Disease Susceptibility bowel disease Signal Transduction Transcription Factors
Zdroj:	Trends in Genetics
ISSN:	0168-9525
Popis:	Not only have helicase-like transcription factor (HLTF) and SNF2 histone-linker PHD-finger RING-finger helicase (SHPRH) proved to be important players in post-replication repair like their yeast counterpart, Rad5, but they are also involved in multiple biological functions and are associated with several human disorders. We provide here an updated view of their functions, associated diseases, and potential therapeutic approaches.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4035420eb3e0bdb58d35951128949a9c https://pubmed.ncbi.nlm.nih.gov/29807746 Zobrazit plný text záznamu Full Text from ScienceDirect