| Autor: |
Downs, Tracy M., Schultzel, Matthew, Shi, Helen, Sanders, Catherine, Tahir, Zunera, Sadler, Georgia Robins |
| Jazyk: |
angličtina |
| Rok vydání: |
2008 |
| Předmět: |
|
| Popis: |
Surgical management of renal cell carcinoma is the most effective treatment for patients with localized disease. In patients with advanced renal cell carcinoma, immune modulation-based therapies are typically used to improve cancer specific survival via anti-angiogenic drugs. Similar to most cancers, tumor grade and stage are linked to the tumor’s biologic potential. Integrating these factors with patients’ performance status can help predict their long-term disease-free survival, the likelihood of tumor recurrence, and the median time to failure following surgery and immunotherapy. A novel integrated staging system and a postoperative renal cell carcinoma specific nomogram, along with standardized quality of life assessments have been shown to be useful clinical tools to aid in patient counseling, determining optimal follow-up imaging protocols, and identifying patients who might benefit from early enrollment in adjuvant therapy protocols. This article offers clinicians a review and summary of the most recent evidence-based research related to risk assessment among patients with newly diagnosed renal cell carcinoma. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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