[Decompactization of chromosome 1 in the artificially decondensed human sperm nuclei: overall topology and non-random location of chromosome bends]
Autor: | O S, Mudrak, N V, Tomilin, A O, Zelenskiĭ |
---|---|
Rok vydání: | 2007 |
Předmět: | |
Zdroj: | Tsitologiia. 49(2) |
ISSN: | 0041-3771 |
Popis: | We have used FISH with microdissected chromosome arm-specific DNA probes that allow direct visualization of chromosome 1 folding in human sperm nuclei. We described the overall topology and the mode of packaging of sperm chromosome 1 and thus established new elements of ordered genome architecture in these specialized cells. |
Databáze: | OpenAIRE |
Externí odkaz: |