[Decompactization of chromosome 1 in the artificially decondensed human sperm nuclei: overall topology and non-random location of chromosome bends]

Autor: O S, Mudrak, N V, Tomilin, A O, Zelenskiĭ
Rok vydání: 2007
Předmět:
Zdroj: Tsitologiia. 49(2)
ISSN: 0041-3771
Popis: We have used FISH with microdissected chromosome arm-specific DNA probes that allow direct visualization of chromosome 1 folding in human sperm nuclei. We described the overall topology and the mode of packaging of sperm chromosome 1 and thus established new elements of ordered genome architecture in these specialized cells.
Databáze: OpenAIRE